• CSIR - Central Salt & Marine Chemicals Research Institute
  • G20
Salt and Marine Chemicals

Title of Process/ Know-how/ Product/Design/Equipment

A process for production of non-hazardous brominating reagent

  • IPR
    IPR Status & Details:
  • US 6,740,253, US 7,459,139
Application/Uses/Problem being addressed

CSMCRI/CSIR has developed a green brominating reagent - a better alternative to the hazardous liquid bromine. This green brominating agent is an attractive source of bromine for bromination of various organic substrates. The reagent has been designed for three main functionalities

  • Brominating reagent for substitution (BR-S);
  • Brominating reagent for addition Reactions (BR-A); and
  • Brominating reagent for oxidations (BR-O). The reagent can be prepared cost-effectively from the intermediate of bromine recovery plants.
    • Salient Technical Features including Competing Features/ Impact
  • Replacement of the corrosive elemental bromine;
  • Safe, easy to handle & transport;
  • Avoids the need of special equipments;
  • Avoids need of catalyst;
  • Maximum bromide atom efficiency;
  • Operates under ambient reaction conditions;
  • Easy to scale-up for the processes development;
  • No formation of hazardous byproducts;
    • TRL Level & Scale of Development:
    TRL 6

    Kg scale preparation

    Business scope & opportunity (in terms of scale, cost, market etc.):

    Bromo-compounds manufacturers

    Environmental Considerations:

    The process does not generate hazardous by-products.

    Status of Licensing:
    Licensed technology
    Status of Commercialization:
    Not yet commercialized
    Major Raw Materials Needed

    Bromine intermediate, chlorine and alkali

    Major Plant Equipment and Machinery Required

    As desired by the customer for the their production.

    Techno-Economics

    The technology is feasible for the large-scale production of green brominating reagents from the intermediate of bromine manufacturing process. The reagent is equivalent (alternate) to liquid bromine in many transformations

    The brominating reagent cost will be approximately equivalent liquid bromine + 20%.

    Technology Package

    Preparation of non-hazardous brominating reagents ; Pilot scale demonstration